Van de Ven Brace Halts Everton's Run at Brand New Home Ground
Micky van de Ven became the initial backline player to score twice in a English top-flight match for Spurs since the Belgian defender in March 2013.
Match summary
Micky Van de Ven nods into the net two times in first half
Everton's defender has goal ruled after video check
Pape Matar Sarr nets final goal in 89th minute
The defeat is Everton's initial at their new ground
The Tottenham defender found the net twice as Tottenham prolonged their unbeaten run in away games in the top division and handed Everton their first defeat at their new home.
Everton were unbeaten in their five previous fixtures at their new ground at the dockside location, having left their historic home behind after more than a century at the conclusion of last season.
But Tottenham's leader Van de Ven pounced twice from set-pieces in the opening 45 minutes to put their impressive record at jeopardy, and they were unable to turn it around before Pape Matar Sarr - assisted by former Toffees attacker the Brazilian - nodded in a final goal to seal the victory.
The Everton defender believed he had levelled the tally a short while after the defender's first goal, glancing a powerful header past the Spurs keeper from an set-piece.
Beto, in the meantime, failed to convert a number of chances, while Vicario made a series of fine stops to guarantee Tottenham went five matches on the road unbeaten in the Premier League.
But the video assistant referee stepped in, advising the match official to review the goal on the pitchside monitor and the official decided that Jack Grealish and the attacker were in an illegal position and had impeded with the Tottenham goalkeeper.
The win moves Thomas Frank's side up to third in the Premier League, five points off north London rivals and leaders Arsenal.
The Merseyside club stay 14th and are half a dozen points clear of the drop zone.
Spurs breakdown: Van de Ven excels in duties at each end of pitch
Following a drab midweek performance in the Champions League against Monaco, where they managed a mere two shots on goal, Frank chose Randal Kolo Muani in attack instead of ex-Everton forward Richarlison.
The new arrival was unable to influence the game before being substituted for Richarlison after 60 minutes on the pitch, but it emerged he wasn't needed in the final outcome.
Defender Van de Ven transformed into an attacking force to be reckoned with.
Tottenham's first goal came from a cleverly executed set-piece play, with the midfielder heading the ball back across the face of goal for an free the defender to score.
And Ven de Ven - stepping up as skipper in the Argentine's absence - notched his next goal in first-half stoppage time as he rose above Jordan Pickford to head home.
The Dutchman was just as outstanding in defensive duties, combining well with Kevin Danso as the pair dealt excellently with the 34 crosses thrown their way by Everton.
Everton analysis: Everton missing finishing touch
The club's recent stadium had been a happy hunting ground, but it appears the freshness may have faded slightly and supporters flocked to the gates after Sarr's final goal for Spurs.
The end in the team's unbeaten home run won't be a massive concern for the manager, but their attacking woes will be.
Beto and Thierno Barry - the Everton's two established centre-forwards - had netted only one league goal combined before Sunday's outing.
And they were failed to add to that poor tally on a wet and gloomy night on in Liverpool.
Beto's form was epitomized when he opted to bicycle-kick a golden opportunity from near the goal, even with having space and opportunity to readjust for a more conventional shot that would have tested Vicario.
The substitute, too, failed to influence the game after coming on for Beto in the second half.
It wasn't for a lack of chance. Most of the home side's attacks came through the winger and the forward, who tirelessly delivered dangerous crosses into the Tottenham penalty area.
What next for both teams?
The Toffees: Moyes' men head to Sunderland in the Premier League on early November at 20:00 GMT.
Spurs: The London club travel to St James' Park on Wednesday, 29 October for their next round Carabao Cup match against the Magpies.